A Kidney-Targeted Nanoparticle to Augment Renal Lymphatic Density Decreases Blood Pressure in Hypertensive Mice

A Kidney-Targeted Nanoparticle to Augment Renal Lymphatic Density Decreases Blood Pressure in Hypertensive Mice

Chronic interstitial inflammation and renal infiltration of activated immune cells play an integral role in hypertension. Lymphatics regulate inflammation through clearance of immune cells and excess interstitial fluid. Previously, we demonstrated increasing renal lymphangiogenesis prevents hyperten...

Full description

Bibliographic Details
Main Authors: Bethany L. Goodlett, Chang Sun Kang, Eunsoo Yoo, Shobana Navaneethabalakrishnan, Dakshnapriya Balasubbramanian, Sydney E. Love, Braden M. Sims, Daniela L. Avilez, Winter Tate, Delilah R. Chavez, Gaurav Baranwal, Mary B. Nabity, Joseph M. Rutkowski, Dongin Kim, Brett M. Mitchell
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Pharmaceutics
Subjects:
kidney
lymphatics
inflammation
immunity
hypertension
Online Access:https://www.mdpi.com/1999-4923/14/1/84

Internet

https://www.mdpi.com/1999-4923/14/1/84

Similar Items