Urokinase plasminogen activator (uPA) and plasminogen activator inhibitor type-1 (PAI-1) in breast cancer - correlation with traditional prognostic factors

Urokinase plasminogen activator (uPA) and plasminogen activator inhibitor type-1 (PAI-1) in breast cancer - correlation with traditional prognostic factors

Background. Urokinase plasminogen activator (uPA) and plasminogen activator inhibitor type-1 (PAI-1) play a key role in tumour invasion and metastasis. High levels of both proteolytic enzymes are associated with poor prognosis in breast cancer patients. The purpose of this study was to evaluate the...

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Bibliographic Details
Main Authors: Lampelj Maja, Arko Darja, Cas-Sikosek Nina, Kavalar Rajko, Ravnik Maja, Jezersek-Novakovic Barbara, Dobnik Sarah, Dovnik Nina Fokter, Takac Iztok
Format: Article
Language:English
Published: Sciendo 2015-12-01
Series:Radiology and Oncology
Subjects:
urokinase plasminogen activator
plasminogen activator inhibitor
breast cancer
prognostic factor
Online Access:https://doi.org/10.2478/raon-2014-0049

Internet

https://doi.org/10.2478/raon-2014-0049

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