Inhibitors of Farnesyl Diphosphate Synthase and Squalene Synthase: Potential Source for Anti-<i>Trypanosomatidae</i> Drug Discovery
Trypanosomatids are mainly responsible for leishmaniasis, sleeping sickness, and Chagas disease, which are the most challenging among the neglected tropical diseases due to the problem of drug resistance. Although problems of target deconvolution and polypharmacology are encountered, a target-based...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2023-08-01
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| Series: | Drugs and Drug Candidates |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2813-2998/2/3/32 |