Sorbitol as a Polar Pharmacological Modifier to Enhance the Hydrophilicity of <sup>99m</sup>Tc-Tricarbonyl-Based Radiopharmaceuticals

Sorbitol as a Polar Pharmacological Modifier to Enhance the Hydrophilicity of <sup>99m</sup>Tc-Tricarbonyl-Based Radiopharmaceuticals

The organometallic technetium-99m tricarbonyl core, [<sup>99m</sup>Tc][Tc(CO)<sub>3</sub>(H<sub>2</sub>O)<sub>3</sub>]<sup>+</sup>, is a versatile precursor for the development of radiotracers for single photon emission computed tomography...

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Bibliographic Details
Main Authors: Carolina Giammei, Theresa Balber, Katarina Benčurová, Jens Cardinale, Neydher Berroterán-Infante, Marie Brandt, Nedra Jouini, Marcus Hacker, Markus Mitterhauser, Thomas L. Mindt
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Molecules
Subjects:
<sup>99m</sup>Tc-tricarbonyl
bombesin
click-to-chelate
glycation
sorbitol
pharmacological modifier
Online Access:https://www.mdpi.com/1420-3049/25/11/2680

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https://www.mdpi.com/1420-3049/25/11/2680

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