Role of sex and sex hormones in PD-L1 expression in NSCLC: clinical and therapeutic implications

Role of sex and sex hormones in PD-L1 expression in NSCLC: clinical and therapeutic implications

Currently, immunotherapy based on PD-1/PD-L1 pathway blockade has improved survival of non-small cell lung cancer (NSCLC) patients. However, differential responses have been observed by sex, where men appear to respond better than women. Additionally, adverse effects of immunotherapy are mainly obse...

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Bibliographic Details
Main Authors: Vianey Rodriguez-Lara, Giovanny Soca-Chafre, Maria Rosa Avila-Costa, Juan Jose Juarez-Vignon Whaley, Jeronimo Rafael Rodriguez-Cid, José Luis Ordoñez-Librado, Emma Rodriguez-Maldonado, Nallely A. Heredia-Jara
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Oncology
Subjects:
NSCLC
PD-1/PD-L1 pathway
immunotherapy
estrogen
androgen
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1210297/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2023.1210297/full

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