Identification and in silico analysis of noval alteration Arg420Gly in KIT proto oncogene among acute myeloid leukemia patients

Abstract A number of studies have reported frequent incidence of c-kit gene mutations in association with core binding factor acute myeloid leukemia (CBF-AML). These genetic changes have become important prognostic predictors in patients with abnormal karyotype. Aim of this study was the detection o...

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Bibliographic Details
Main Authors: Afia Muhammad Akram, Mubashir Hassan, Asma Chaudhary, Sikandar Hayat, Qurban Ali, Taha Hussain, Amjad Zafar, Muhammad Arshad Javed
Format: Article
Language:English
Published: Nature Portfolio 2022-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-23934-y