Understanding the Adsorption of Peptides and Proteins onto PEGylated Gold Nanoparticles

Understanding the Adsorption of Peptides and Proteins onto PEGylated Gold Nanoparticles

Polyethylene glycol (PEG) surface conjugations are widely employed to render passivating properties to nanoparticles in biological applications. The benefits of surface passivation by PEG are reduced protein adsorption, diminished non-specific interactions, and improvement in pharmacokinetics. Howev...

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Bibliographic Details
Main Authors: Yasiru Randika Perera, Joanna Xiuzhu Xu, Dhanush L. Amarasekara, Alex C. Hughes, Ibraheem Abbood, Nicholas C. Fitzkee
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Molecules
Subjects:
NMR spectroscopy
gold nanoparticles
PEGylation
adsorption
passivation
Online Access:https://www.mdpi.com/1420-3049/26/19/5788

Internet

https://www.mdpi.com/1420-3049/26/19/5788

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