Does Chronic Sleep Fragmentation Lead to Alzheimer's Disease in Young Wild-Type Mice?

Does Chronic Sleep Fragmentation Lead to Alzheimer's Disease in Young Wild-Type Mice?

Chronic sleep insufficiency is becoming a common issue in the young population nowadays, mostly due to life habits and work stress. Studies in animal models of neurological diseases reported that it would accelerate neurodegeneration progression and exacerbate interstitial metabolic waste accumulati...

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Bibliographic Details
Main Authors: Li Ba, Lifang Huang, Ziyu He, Saiyue Deng, Yi Xie, Min Zhang, Cornelius Jacob, Emanuele Antonecchia, Yuqing Liu, Wenchang Xiao, Qingguo Xie, Zhili Huang, Chenju Yi, Nicola D'Ascenzo, Fengfei Ding
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-12-01
Series:Frontiers in Aging Neuroscience
Subjects:
sleep fragmentation
Alzheimer's disease
stress
F-18-fluorodeoxyglucose-positron emission tomography (18F-FDG-PET)
neuroinflammation
tau
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2021.759983/full

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https://www.frontiersin.org/articles/10.3389/fnagi.2021.759983/full

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