The Combination of Human Urinary Kallidinogenase and Mild Hypothermia Protects Adult Rats Against Hypoxic-Ischemic Encephalopathy-Induced Injury by Promoting Angiogenesis and Regeneration

The Combination of Human Urinary Kallidinogenase and Mild Hypothermia Protects Adult Rats Against Hypoxic-Ischemic Encephalopathy-Induced Injury by Promoting Angiogenesis and Regeneration

Objectives: Human Urinary Kallidinogenase (HUK) is a tissue kallikrein that plays neuroprotective role in ischemic conditions via different mechanisms. Mild hypothermia (MH) is another robust neuroprotectant that reduces mortality but does not profoundly ameliorate the neurological outcome in hypoxi...

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Bibliographic Details
Main Authors: Xiaoya Gao, Haiting Xie, Shuzhen Zhu, Bin Yu, Ying Xian, Qian Ouyang, Yabin Ji, Xiaohua Yang, Chunyan Wen, Penghua Wang, Yufeng Tong, Qing Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Aging Neuroscience
Subjects:
hypoxic-ischemic encephalopathy
neuroprotectant
human urinary kallidinogenase
mild hypothermia
angiogenesis
regeneration
Online Access:https://www.frontiersin.org/article/10.3389/fnagi.2018.00196/full

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https://www.frontiersin.org/article/10.3389/fnagi.2018.00196/full

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