Transcriptomic profiling highlights cell proliferation in the progression of experimental pulmonary hypertension in rats

Transcriptomic profiling highlights cell proliferation in the progression of experimental pulmonary hypertension in rats

Abstract Pulmonary arterial hypertension (PAH) is a progressive disease characterized by pulmonary vascular remolding and occlusion, leading to the elevated pulmonary arterial pressures, right ventricular hypertrophy, and eventual heart failure if left untreated. Understanding the molecular mechanis...

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Bibliographic Details
Main Authors: Ang Luo, Rongrong Hao, Xia Zhou, Yangfan Jia, Changlei Bao, Lei Yang, Lirong Zhou, Chenxin Gu, Ankit A. Desai, Haiyang Tang, Ai-ai Chu
Format: Article
Language:English
Published: Nature Portfolio 2024-06-01
Series:Scientific Reports
Subjects:
Pulmonary arterial hypertension
RNA sequencing
Cell proliferation
Online Access:https://doi.org/10.1038/s41598-024-64251-w

Internet

https://doi.org/10.1038/s41598-024-64251-w

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