Prenatal Choline Supplementation Alters One Carbon Metabolites in a Rat Model of Periconceptional Alcohol Exposure

Prenatal Choline Supplementation Alters One Carbon Metabolites in a Rat Model of Periconceptional Alcohol Exposure

Prenatal alcohol exposure disturbs fetal and placental growth and can alter DNA methylation (DNAm). Supplementation with the methyl donor choline can increase fetal and placental growth and restore DNAm, suggesting converging effects on one-carbon metabolism (1CM). We investigated the impact of peri...

Full description

Bibliographic Details
Main Authors:	Sarah E. Steane, Vinod Kumar, James S. M. Cuffe, Karen M. Moritz, Lisa K. Akison
Format:	Article
Language:	English
Published:	MDPI AG 2022-04-01
Series:	Nutrients
Subjects:	methyl group one carbon metabolism prenatal alcohol maternal nutrition placenta mass spectrometry
Online Access:	https://www.mdpi.com/2072-6643/14/9/1874

Similar Items

The Impacts of Periconceptional Alcohol on Neonatal Ovaries and Subsequent Adult Fertility in the Rat
by: Sarah E. Steane, et al.
Published: (2024-02-01)

Independent and Combined Effects of Prenatal Alcohol Exposure and Prenatal Stress on Fetal HPA Axis Development
by: Ludmila N. Bakhireva, et al.
Published: (2024-02-01)

Maternal DHA supplementation influences sex-specific disruption of placental gene expression following early prenatal stress
by: Eldin Jašarević, et al.
Published: (2021-01-01)

Social behavior of offspring following prenatal cocaine exposure in rodents: a comparison with prenatal alcohol
by: Sonya Krishna Sobrian, et al.
Published: (2011-11-01)

Chromatin modifier developmental pluripotency associated factor 4 (DPPA4) is a candidate gene for alcohol-induced developmental disorders
by: P. Auvinen, et al.
Published: (2022-12-01)

Increasing the prepartum dose of rumen-protected choline: Effects of maternal choline supplementation on growth, feed efficiency, and metabolism in Holstein and Holstein × Angus calves
by: H.T. Holdorf, et al.
Published: (2023-09-01)

Potential Serum Biomarkers in Prenatal Diagnosis of Placenta Accreta Spectrum
by: Tianyue Zhang, et al.
Published: (2022-05-01)

Prenatal Alcohol Exposure and Child Psychosocial Behavior: A Sibling Fixed-Effects Analysis
by: Kayoko Ichikawa, et al.
Published: (2018-11-01)

Postnatal Choline Supplementation Rescues Deficits in Synaptic Plasticity Following Prenatal Ethanol Exposure
by: Erin L. Grafe, et al.
Published: (2022-05-01)

ESTRÉS PRENATAL Y SUS EFECTOS SOBRE EL NEURODESARROLLO
by: Dr. Rodrigo Díaz, et al.
Published: (2016-07-01)

Placental microRNAs: Responders to environmental chemicals and mediators of pathophysiology of the human placenta
by: Kezia A. Addo, et al.
Published: (2020-01-01)

Prenatal and Postnatal Choline Supplementation in Fetal Alcohol Spectrum Disorder
by: Abigail M. Ernst, et al.
Published: (2022-02-01)

Mechanisms Underlying Cognitive Impairment Induced by Prenatal Alcohol Exposure
by: Ahmad Alhowail
Published: (2022-12-01)

Risk of malaria in young children after periconceptional iron supplementation
by: Sabine Gies, et al.
Published: (2021-04-01)

Hippocampal DNA Methylation in a Mouse Model of Fetal Alcohol Spectrum Disorder That Includes Maternal Separation Stress Only Partially Explains Changes in Gene Expression
by: Bonnie L.J. Alberry, et al.
Published: (2020-02-01)

Periconceptional alcohol exposure causes female-specific perturbations to trophoblast differentiation and placental formation in the rat
by: Kalisch-Smith, J, et al.
Published: (2019)

Mitochondrial DNA methylation in placental tissue: a proof of concept study by means of prenatal environmental stressors
by: Stijn Vos, et al.
Published: (2021-02-01)

Polymethylation scores for prenatal maternal smoke exposure persist until age 15 and are detected in saliva in the Fragile Families and Child Wellbeing cohort
by: Freida A. Blostein, et al.
Published: (2022-12-01)

Prenatal Environmental Stressors and DNA Methylation Levels in Placenta and Peripheral Tissues of Mothers and Neonates Evaluated by Applying Artificial Neural Networks
by: Andrea Stoccoro, et al.
Published: (2023-03-01)

Prenatal alcohol exposure alters mRNA expression for stress peptides, glucocorticoid receptor function and immune factors in acutely stressed neonatal brain
by: Chaselyn D. Ruffaner-Hanson, et al.
Published: (2023-06-01)

Impact of prenatal alcohol exposure on neurodevelopmental outcomes: a systematic review
by: Joanna Ting Wai Chu, et al.
Published: (2022-12-01)

Why pregnant women delay prenatal care?
by: Hasan, M
Published: (1998-05-01)

Prenatal alcohol history – setting a threshold for diagnosis requires a level of detail and accuracy that does not exist
by: Susan Petryk, et al.
Published: (2019-10-01)

Effect of Prenatal Opioid Exposure on the Human Placental Methylome
by: Kristyn N. Borrelli, et al.
Published: (2022-05-01)

Choline Plus Working Memory Training Improves Prenatal Alcohol-Induced Deficits in Cognitive Flexibility and Functional Connectivity in Adulthood in Rats
by: Jaylyn Waddell, et al.
Published: (2020-11-01)

Acute and Protracted Prenatal Stress Produce Mood Disorder-Like and Ethanol Drinking Behaviors in Male and Female Adult Offspring
by: Erbo Dong, et al.
Published: (2022-05-01)

Symptoms of Prenatal Depression Associated with Shorter Telomeres in Female Placenta
by: Isabel Garcia-Martin, et al.
Published: (2021-07-01)

Prenatal alcohol exposure in rodents as a promising model for the study of ADHD molecular basis.
by: Argelia Esperanza Rojas-Mayorquin, et al.
Published: (2016-12-01)

Prenatal Alcohol Exposure as a Case of Involuntary Early Onset of Alcohol Use: Consequences and Proposed Mechanisms From Animal Studies
by: Mirari Gaztañaga, et al.
Published: (2020-03-01)

A critical evaluation of prenatal supplements: Are they meeting the mark?
by: Mayur B Wanjari, et al.
Published: (2023-01-01)

Ultrasound scoring system for prenatal diagnosis of placenta accreta spectrum
by: Junling Zhang, et al.
Published: (2023-08-01)

Knowledge, attitudes, practices, and beliefs regarding prenatal alcohol consumption among women in Leyte, the Philippines
by: Alice M. Huang, et al.
Published: (2023-08-01)

Maternal Perspectives of Prenatal Sonogram in a North-Eastern Population in Nigeria
by: Ugwu AC, et al.
Published: (2009-01-01)

Prenatal Hypoxia Affects Foetal Cardiovascular Regulatory Mechanisms in a Sex- and Circadian-Dependent Manner: A Review
by: Hana Sutovska, et al.
Published: (2022-03-01)

Concerns and Strengths: Caregiver Perceptions of Their Infant/Toddler with Prenatal Alcohol Exposure
by: Misty Pruner, et al.
Published: (2023-03-01)

Care Practices Supporting Prenatal Attachment
by: Aysun Ünal, et al.
Published: (2021-12-01)

Sex-Related Differences in Voluntary Alcohol Intake and mRNA Coding for Synucleins in the Brain of Adult Rats Prenatally Exposed to Alcohol
by: Viktor S. Kokhan, et al.
Published: (2022-09-01)

The Early Developmental Outcomes of Prenatal Alcohol Exposure: A Review
by: Sivenesi Subramoney, et al.
Published: (2018-12-01)

Selenium supplementation within the periconception period: Influence on maternal liver and renal histoarchitecture
by: Mark Anthony C. Mamon, et al.
Published: (2016-07-01)

Maternal obesity influences expression and DNA methylation of the adiponectin and leptin systems in human third-trimester placenta
by: Perrine Nogues, et al.
Published: (2019-02-01)