Neuronal and synaptic adaptations underlying the benefits of deep brain stimulation for Parkinson's disease

Abstract Deep brain stimulation (DBS) is a well-established and effective treatment for patients with advanced Parkinson's disease (PD), yet its underlying mechanisms remain enigmatic. Optogenetics, primarily conducted in animal models, provides a unique approach that allows cell type- and proj...

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Bibliographic Details
Main Authors: Wenying Xu, Jie Wang, Xin-Ni Li, Jingxue Liang, Lu Song, Yi Wu, Zhenguo Liu, Bomin Sun, Wei-Guang Li
Format: Article
Language:English
Published: BMC 2023-11-01
Series:Translational Neurodegeneration
Subjects:
Online Access:https://doi.org/10.1186/s40035-023-00390-w