Fenofibrate attenuates renal lipotoxicity in uninephrectomized mice with high-fat diet-induced obesity

Fenofibrate attenuates renal lipotoxicity in uninephrectomized mice with high-fat diet-induced obesity

Abstract Introduction: The objective of this study was to investigate the role of fenofibrate, a peroxisome proliferator-activated receptor-α agonist, in obesity-induced kidney damage (lipotoxicity) in mice with uninephrectomy. Methods: C57BL/6 mice underwent uninephrectomy and sham surgeries and...

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Bibliographic Details
Main Authors: Barbara Bruna Abreu Castro, Petrus Ferreira Reno, Bianca Fatima Pereira, Kaique Arriel, Fabiana Bastos Bonato, Fernando Antonio Basile Colugnati, Marcos Antonio Cenedeze, Niels Olsen Saraiva-Camara, Helady Sanders-Pinheiro
Format: Article
Language:English
Published: Sociedade Brasileira de Nefrologia 2024-09-01
Series:Brazilian Journal of Nephrology
Subjects:
Lipid Metabolism Disorders
Obesity
Nephrectomy
PPAR alpha
Fibroblast Growth Factors
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0101-28002024000400307&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0101-28002024000400307&lng=en&tlng=en

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