Immunomodulatory Responses of Subcapsular Sinus Floor Lymphatic Endothelial Cells in Tumor-Draining Lymph Nodes

Immunomodulatory Responses of Subcapsular Sinus Floor Lymphatic Endothelial Cells in Tumor-Draining Lymph Nodes

Tumor-draining lymph nodes (LNs), composed of lymphocytes, antigen-presenting cells, and stromal cells, are highly relevant for tumor immunity and the efficacy of immunotherapies. Lymphatic endothelial cells (LECs) represent an important stromal cell type within LNs, and several distinct subsets of...

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Bibliographic Details
Main Authors: Eliane Sibler, Yuliang He, Luca Ducoli, Viviane Rihs, Patrick Sidler, Claudia Puig-Moreno, Jasmin Frey, Noriki Fujimoto, Michael Detmar, Lothar C. Dieterich
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Cancers
Subjects:
cancer
melanoma
scRNA-seq
lymph node
lymphatic endothelial cells
macrophage
Online Access:https://www.mdpi.com/2072-6694/14/15/3602

Internet

https://www.mdpi.com/2072-6694/14/15/3602

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