Decreased β-catenin expression contributes to IFNγ-induced chemokine secretion and lymphocyte infiltration in Hashimoto’s thyroiditis

Hashimoto’s thyroiditis (HT) is a very common organ-specific aut oimmune disease characterized by lymphocyte infiltration and the destruction of thyroid follicular cells (TFCs), in which IFN-γ and chemokines play pivotal roles. Moreover, β-catenin has been implicated in the regulation of T cell in f...

Full description

Bibliographic Details
Main Authors: Fei Wu, Chaoming Mao, Xiao Mou, Chengcheng Xu, Tingting Zheng, Ling Bu, Xuan Luo, Qingyan Lu, Xuefeng Wang
Format: Article
Language:English
Published: Bioscientifica 2022-03-01
Series:Endocrine Connections
Subjects:
Online Access:https://ec.bioscientifica.com/view/journals/ec/11/2/EC-21-0451.xml