Association of plasma level of high-mobility group box-1 with necroptosis and sepsis outcomes

Abstract The role of high-mobility group box-1 (HMGB1) in outcome prediction in sepsis is controversial. Furthermore, its association with necroptosis, a programmed cell necrosis mechanism, is still unclear. The purpose of this study is to identify the association between the plasma levels of HMGB1...

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Bibliographic Details
Main Authors: Hongseok Yoo, Yunjoo Im, Ryoung-Eun Ko, Jin Young Lee, Junseon Park, Kyeongman Jeon
Format: Article
Language:English
Published: Nature Portfolio 2021-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-88970-6