Pellino-1 Regulates Immune Responses to Haemophilus influenzae in Models of Inflammatory Lung Disease

Pellino-1 Regulates Immune Responses to Haemophilus influenzae in Models of Inflammatory Lung Disease

Non-typeable Haemophilus influenzae (NTHi) is a frequent cause of lower respiratory tract infection in people with chronic obstructive pulmonary disease (COPD). Pellino proteins are a family of E3 ubiquitin ligases that are critical regulators of TLR signaling and inflammation. The aim of this study...

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Bibliographic Details
Main Authors: Bethany M. Hughes, Charlotte S. Burton, Abigail Reese, Maisha F. Jabeen, Carl Wright, Jessica Willis, Nika Khoshaein, Elizabeth K. Marsh, Peter Peachell, Shao C. Sun, David H. Dockrell, Helen M. Marriott, Ian Sabroe, Alison M. Condliffe, Lynne R. Prince
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Immunology
Subjects:
Haemophilus influenzae
Pellino-1
immunity
lung
inflammation
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01721/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.01721/full

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