Changes in Striatal Medium Spiny Neuron Morphology Resulting from Dopamine Depletion Are Reversible

The classical motor symptoms of Parkinson’s disease (PD) are caused by degeneration of dopaminergic neurons in the substantia nigra, which is followed by secondary dendritic pruning and spine loss at striatal medium spiny neurons (MSN). We hypothesize that these morphological changes at MSN underlie...

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Detaylı Bibliyografya
Asıl Yazarlar: Victoria Sofie Witzig, Daniel Komnig, Björn H. Falkenburger
Materyal Türü: Makale
Dil:English
Baskı/Yayın Bilgisi: MDPI AG 2020-11-01
Seri Bilgileri:Cells
Konular:
Online Erişim:https://www.mdpi.com/2073-4409/9/11/2441