BMP9‐induced vascular normalisation improves the efficacy of immunotherapy against hepatitis B virus‐associated hepatocellular carcinoma

BMP9‐induced vascular normalisation improves the efficacy of immunotherapy against hepatitis B virus‐associated hepatocellular carcinoma

Abstract Background In the past decade, the field of tumour immunotherapy has made a great progress. However, the efficacy of immune checkpoint blocking (ICB) in the treatment of hepatocellular carcinoma (HCC) remains limited. Cytotoxic lymphocyte trafficking into tumours is critical for the success...

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Main Authors: Yulong Han, Qiuzhong Pan, Zhixing Guo, Yufei Du, Yaojun Zhang, Yingying Liu, Jingjing Zhao, Jinfeng Xu, Jieying Yang, Dijun Ouyang, Yan Tang, Qijing Wang, Yongqiang Li, Jia He, Mengjuan Yang, Hao Chen, Chaopin Yang, Xinyi Yang, Jinqi You, Yuanyuan Chen, Minghao Ren, Yao Zhu, Jianchuan Xia, Tong Xiang
Format: Article
Language:English
Published: Wiley 2023-05-01
Series:Clinical and Translational Medicine
Subjects:
BMP9
HBV‐associated HCC
immunotherapy
vascular normalisation
Online Access:https://doi.org/10.1002/ctm2.1247

Internet

https://doi.org/10.1002/ctm2.1247

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