Altered Transcriptional Regulation of Glycolysis in Circulating CD8<sup>+</sup> T Cells of Rheumatoid Arthritis Patients

Altered Transcriptional Regulation of Glycolysis in Circulating CD8<sup>+</sup> T Cells of Rheumatoid Arthritis Patients

Peripheral T lymphocytes of rheumatoid arthritis (RA) patients show pathological changes in their metabolic pathways, especially glycolysis. These changes may drive the increased proliferation and tissue invasiveness of RA T cells. In order to study the transcriptional regulation underlying these al...

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Bibliographic Details
Main Authors: Shilpa Harshan, Poulami Dey, Srivatsan Raghunathan
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Genes
Subjects:
rheumatoid arthritis
T lymphocyte
regulation of glycolysis
RNA sequencing
<i>PFKFB3</i>
pentose phosphate pathway
Online Access:https://www.mdpi.com/2073-4425/13/7/1216

Internet

https://www.mdpi.com/2073-4425/13/7/1216

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