Laminins in tumor-derived exosomes upregulated by ETS1 reprogram omental macrophages to promote omental metastasis of ovarian cancer

Abstract Tumor-derived exosomes participate in omental metastatic colonization of ovarian cancer by inducing an adaptive response in the tumor microenvironment. However, cell–cell communication via exosomes between primary tumor cells and the microenvironment of distant omentum and the mechanism of...

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Bibliographic Details
Main Authors: Haiyang Li, Cheng Zeng, Chang Shu, Yuanyuan Cao, Wengui Shao, Mengjie Zhang, Hongyong Cao, Shuli Zhao
Format: Article
Language:English
Published: Nature Publishing Group 2022-12-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-022-05472-7