Local IGFBP-3 mRNA expression, apoptosis and risk of colorectal adenomas

Local IGFBP-3 mRNA expression, apoptosis and risk of colorectal adenomas

<p>Abstract</p> <p>Background</p> <p>IGF binding protein-3 (IGFBP-3) regulates the bioavailability of insulin-like growth factors I and II, and has both anti-proliferative and pro-apoptotic properties. Elevated plasma IGFBP-3 has been associated with reduced risk of col...

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Bibliographic Details
Main Authors: Omofoye Oluwaseun, Proffitt Michelle, Woosley John T, Galanko Joseph, Simmons James G, Sandler Robert S, Keku Temitope O, McDoom Maya, Lund Pauline K
Format: Article
Language:English
Published: BMC 2008-05-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/8/143

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http://www.biomedcentral.com/1471-2407/8/143

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