Unraveling the interplay between PKA inhibition and Cdk1 activation during oocyte meiotic maturation
Summary: Oocytes are arrested in prophase I. In vertebrates, meiotic resumption is triggered by hormonal stimulation that results in cAMP-dependent protein kinase (PKA) downregulation leading to Cdk1 activation. Yet the pathways connecting PKA to Cdk1 remain unclear. Here, we identify molecular even...
| Hauptverfasser: | , , , , , , |
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| Format: | Artikel |
| Sprache: | English |
| Veröffentlicht: |
Elsevier
2024-02-01
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| Schriftenreihe: | Cell Reports |
| Schlagworte: | |
| Online Zugang: | http://www.sciencedirect.com/science/article/pii/S2211124724001104 |