Antimicrobial evaluation of spirooxindolopyrrolidine engrafted indoles against multidrug resistant ESKAPE clinical pathogens

The synthesis of a new class of effective antibiotics and antimicrobial agents with less toxicity is highly desirable due to bacterial resistance to antibiotics has increased dramatically. In this context, molecules that embedding a spiro moiety are attractive from a medicinal chemistry point of vie...

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Bibliographic Details
Main Authors: Natarajan Arumugam, Khloud Ibrahim Al-Shemaimari, Mohammad Altaf, Karuppiah Ponmurugan, Dhanaraj Premnath, Sinouvassane Djearamane, Ling Shing Wong, Saminathan Kayarohanam
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Journal of King Saud University: Science
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1018364723004585