Gold nanoparticle-directed autophagy intervention for antitumor immunotherapy via inhibiting tumor-associated macrophage M2 polarization

Gold nanoparticle-directed autophagy intervention for antitumor immunotherapy via inhibiting tumor-associated macrophage M2 polarization

Tumor-associated macrophages (TAMs), one of the dominating constituents of tumor microenvironment, are important contributors to cancer progression and treatment resistance. Therefore, regulation of TAMs polarization from M2 phenotype towards M1 phenotype has emerged as a new strategy for tumor immu...

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Bibliographic Details
Main Authors: Siyue Zhang, Fangyuan Xie, Kaichun Li, He Zhang, You Yin, Yuan Yu, Guangzhao Lu, Shihao Zhang, Yan Wei, Ke Xu, Yan Wu, Hong Jin, Lan Xiao, Leilei Bao, Can Xu, Yulin Li, Ying Lu, Jie Gao
Format: Article
Language:English
Published: Elsevier 2022-07-01
Series:Acta Pharmaceutica Sinica B
Subjects:
Macrophage polarization
Tumor-associated macrophages
Nanomaterials
Autophagy flux
Lysosomal damage
Gold nanoparticles
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383522000582

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http://www.sciencedirect.com/science/article/pii/S2211383522000582

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