Chemotherapy promotes astrocytic response to Aβ deposition, but not Aβ levels, in a mouse model of amyloid and APOE

Many cancer survivors experience cancer-related cognitive impairment (CRCI), which is characterized by problems of attention, working memory, and executive function following chemotherapy and/or hormonal treatment. APOE4, the strongest genetic risk factor for Alzheimer's Disease (AD), is also a...

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Bibliographic Details
Main Authors: Christi Anne S. Ng, Lucas P. Biran, Elena Galvano, Jeanne Mandelblatt, Stefano Vicini, G. William Rebeck
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996122003072