The Role of PIK3R1 in Metabolic Function and Insulin Sensitivity

The Role of PIK3R1 in Metabolic Function and Insulin Sensitivity

PIK3R1 (also known as p85α) is a regulatory subunit of phosphoinositide 3-kinases (PI3Ks). PI3K, a heterodimer of a regulatory subunit and a catalytic subunit, phosphorylates phosphatidylinositol into secondary signaling molecules involved in regulating metabolic homeostasis. PI3K converts phosphati...

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Bibliographic Details
Main Authors: Ariel Tsay, Jen-Chywan Wang
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:International Journal of Molecular Sciences
Subjects:
phosphoinositide 3-kinases (PI3K)
PIK3R1
p85α, insulin signaling
insulin resistance
type 2 diabetes
metabolic disorders
Online Access:https://www.mdpi.com/1422-0067/24/16/12665

Internet

https://www.mdpi.com/1422-0067/24/16/12665

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