Suppressive Effects of Isofraxidin on Depressive-like Behaviors Induced by Chronic Unpredictable Mild Stress in Mice

Suppressive Effects of Isofraxidin on Depressive-like Behaviors Induced by Chronic Unpredictable Mild Stress in Mice

Isofraxidin is an active component of several traditional and functional plants that have beneficial properties for neurodegenerative diseases. In this study, we examined whether isofraxidin exhibited antidepressant-like effects in chronic unpredictable mild stress (CUMS)-induced mice. Firstly, isof...

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Bibliographic Details
Main Authors: Xiaoli Wu, Jingwen Gu, Zhicong Zou, Meng Yu, Chen Zhang, Qinghui Xiao, Xin Chen, Chuwen Li
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Brain Sciences
Subjects:
isofraxidin
depression
CUMS
HPA axis
neuroinflammation
NF-κB-NLRP3 inflammasomes
Online Access:https://www.mdpi.com/2076-3425/12/10/1376

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https://www.mdpi.com/2076-3425/12/10/1376

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