Ca2+-currents in human induced pluripotent stem cell-derived cardiomyocytes - effects of two different culture conditions

Ca2+-currents in human induced pluripotent stem cell-derived cardiomyocytes - effects of two different culture conditions

Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CM) provide a unique opportunity to study human heart physiology and pharmacology and repair injured hearts. The suitability of hiPSC-CM critically depends on how closely they share physiological properties of human adult cardiomyocyt...

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Bibliographic Details
Main Authors: Ahmet Umur Uzun, Ingra Mannhardt, Kaja Breckwoldt, András Horváth, Silke Skytte Johannsen, Arne Hansen, Thomas Eschenhagen, Torsten Christ
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-09-01
Series:Frontiers in Pharmacology
Subjects:
5-Hydroxytryptamine
protein kinase A
β-adrenoceptor
L-type Ca2+-channel
Human induced pluripotent stem cell-derived cardiomyocytes
T-type Ca2+-channel
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2016.00300/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphar.2016.00300/full

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