Treatment of vocal fold scarring with autologous bone marrow-derived human mesenchymal stromal cells—first phase I/II human clinical study

Treatment of vocal fold scarring with autologous bone marrow-derived human mesenchymal stromal cells—first phase I/II human clinical study

Abstract Background Vocal fold (VF) scarring, caused by surgery or inflammation, often results in severe voice problems or aphonia. Effective lasting treatment is lacking. Previous in vitro and in vivo animal studies reported positive effects on VF scar resolution with mesenchymal stromal cell (MSC)...

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Bibliographic Details
Main Authors: Stellan Hertegård, Srinivasa Rau Nagubothu, Emma Malmström, Katarina LeBlanc
Format: Article
Language:English
Published: BMC 2020-03-01
Series:Stem Cell Research & Therapy
Subjects:
Vocal fold
Scarring
Hoarseness
Mesenchymal stromal cells
Fibrosis
Immunomodulation
Online Access:http://link.springer.com/article/10.1186/s13287-020-01632-8

Internet

http://link.springer.com/article/10.1186/s13287-020-01632-8

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