The Modulation of Cellular Susceptibility to Oxidative Stress: Protective and Destructive Actions of Cu,Zn-Superoxide Dismutase
Alterations in the activity of Cu,Zn-superoxide dismutase (SOD1), an enzyme that converts superoxide (O·−2) to hydrogen peroxide (H2O2) plus O2, have been found to affect cellular susceptibility to oxidative stress and have been invoked as a pathogenetic mechanism in a variety of neurodegenerative d...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2002-08-01
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| Series: | Neurobiology of Disease |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0969996102905048 |