Reduced Virus Load in Lungs of Pigs Challenged with Porcine Reproductive and Respiratory Syndrome Virus after Vaccination with Virus Replicon Particles Encoding Conserved PRRSV Cytotoxic T-Cell Epitopes

Reduced Virus Load in Lungs of Pigs Challenged with Porcine Reproductive and Respiratory Syndrome Virus after Vaccination with Virus Replicon Particles Encoding Conserved PRRSV Cytotoxic T-Cell Epitopes

Porcine reproductive and respiratory syndrome virus (PRRSV) causes severe respiratory distress and reproductive failure in swine. Modified live virus (MLV) vaccines provide the highest degree of protection and are most often the preferred choice. While somewhat protective, the use of MLVs is accompa...

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Bibliographic Details
Main Authors: Simon Welner, Nicolas Ruggli, Matthias Liniger, Artur Summerfield, Lars Erik Larsen, Gregers Jungersen
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Vaccines
Subjects:
porcine reproductive and respiratory syndrome virus (PRRSV)
virus replicon particles (VRP)
classical swine fever virus (CSFV)
viral vector
vaccine
polyepitope antigen
Online Access:https://www.mdpi.com/2076-393X/9/3/208

Internet

https://www.mdpi.com/2076-393X/9/3/208

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