Proximal tubular hypertrophy and enlarged glomerular and proximal tubular urinary space in obese subjects with proteinuria.

BACKGROUND: Obesity is associated with glomerular hyperfiltration, increased proximal tubular sodium reabsorption, glomerular enlargement and renal hypertrophy. A single experimental study reported an increased glomerular urinary space in obese dogs. Whether proximal tubular volume is increased in o...

Full description

Bibliographic Details
Main Authors: Ana Tobar, Yaacov Ori, Sydney Benchetrit, Gai Milo, Michal Herman-Edelstein, Boris Zingerman, Netta Lev, Uzi Gafter, Avry Chagnac
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3783420?pdf=render