Case report: Better late than never, but sooner is better: switch from CSII to sulfonylureas in two patients with neonatal diabetes due to KCNJ11 variants

Case report: Better late than never, but sooner is better: switch from CSII to sulfonylureas in two patients with neonatal diabetes due to KCNJ11 variants

Neonatal diabetes mellitus (NDM) is a rare genetic disease characterized by severe hyperglycemia requiring insulin therapy with onset mostly within the first 6 months and rarely between 6-12 months of age. The disease can be classified into transient (TNDM) or permanent neonatal diabetes mellitus (P...

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Bibliographic Details
Main Authors: Valentina Mancioppi, Erica Pozzi, Sara Zanetta, Anna Missineo, Silvia Savastio, Fabrizio Barbetti, Simona Mellone, Mara Giordano, Ivana Rabbone
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Endocrinology
Subjects:
neonatal diabetes mellitus (NDM)
monogenic diabetes
KCNJ11
continuous subcutaneous insulin infusion (CSII)
glibenclamide
hyperglycemia
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2023.1143736/full

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https://www.frontiersin.org/articles/10.3389/fendo.2023.1143736/full

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