Identifying quantitatively differential chromosomal compartmentalization changes and their biological significance from Hi-C data using DARIC
Abstract Background Chromosomal compartmentalization plays a critical role in maintaining proper transcriptional programs in cell differentiation and oncogenesis. However, currently the prevalent method for comparative analysis of compartmentalization landscapes between different cell types is limit...
Main Authors: | , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2023-10-01
|
Series: | BMC Genomics |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12864-023-09675-w |