Identifying quantitatively differential chromosomal compartmentalization changes and their biological significance from Hi-C data using DARIC

Identifying quantitatively differential chromosomal compartmentalization changes and their biological significance from Hi-C data using DARIC

Abstract Background Chromosomal compartmentalization plays a critical role in maintaining proper transcriptional programs in cell differentiation and oncogenesis. However, currently the prevalent method for comparative analysis of compartmentalization landscapes between different cell types is limit...

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Bibliografiska uppgifter
Huvudupphovsmän: Yan Kai, Nan Liu, Stuart H. Orkin, Guo-Cheng Yuan
Materialtyp: Artikel
Språk:English
Publicerad: BMC 2023-10-01
Serie:BMC Genomics
Ämnen:
Compartment
Compartmentalization
Hi-C
3D genome
Gene regulation
Nuclear positioning
Länkar:https://doi.org/10.1186/s12864-023-09675-w

Internet

https://doi.org/10.1186/s12864-023-09675-w

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