Interleukin-6 actions in the hypothalamus protects against obesity and is involved in the regulation of neurogenesis

Abstract Background Interleukin-6 (IL6) produced in the context of exercise acts in the hypothalamus reducing obesity-associated inflammation and restoring the control of food intake and energy expenditure. In the hippocampus, some of the beneficial actions of IL6 are attributed to its neurogenesis-...

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Main Authors: Vanessa C. Bobbo, Daiane F. Engel, Carlos Poblete Jara, Natalia F. Mendes, Roberta Haddad-Tovolli, Thais P. Prado, Davi Sidarta-Oliveira, Joseane Morari, Licio A. Velloso, Eliana P. Araujo
Format: Article
Language:English
Published: BMC 2021-08-01
Series:Journal of Neuroinflammation
Subjects:
Online Access:https://doi.org/10.1186/s12974-021-02242-8