The emerging and diverse roles of F-box proteins in spermatogenesis and male infertility

The emerging and diverse roles of F-box proteins in spermatogenesis and male infertility

Abstract F-box proteins play essential roles in various cellular processes of spermatogenesis by means of ubiquitylation and subsequent target protein degradation. They are the substrate-recognition subunits of SKP1–cullin 1–F-box protein (SCF) E3 ligase complexes. Dysregulation of F‑box protein‑med...

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Bibliographic Details
Main Authors: Xuan Zhuang, Jun Ruan, Canquan Zhou, Zhiming Li
Format: Article
Language:English
Published: SpringerOpen 2024-06-01
Series:Cell Regeneration
Subjects:
F-box proteins
Ubiquitylation
Spermatogenesis
Male infertility
Male germ cells
Online Access:https://doi.org/10.1186/s13619-024-00196-9

Internet

https://doi.org/10.1186/s13619-024-00196-9

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