Effect of doxycycline in patients of moderate to severe chronic obstructive pulmonary disease with stable symptoms

Effect of doxycycline in patients of moderate to severe chronic obstructive pulmonary disease with stable symptoms

Background: The protease-antiprotease hypothesis proposes that inflammatory cells and oxidative stress in chronic obstructive pulmonary disease (COPD) produce increased levels of proteolytic enzymes (neutrophil elastase, matrix metalloproteinases [MMP]) which contribute to destruction of parenchyma...

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Bibliographic Details
Main Authors: Prashant S Dalvi, Anil Singh, Hiren R Trivedi, Feroz D Ghanchi, Dinesh M Parmar, Suresh D Mistry
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2011-01-01
Series:Annals of Thoracic Medicine
Subjects:
Anti-inflammatory
C-reactive protein
doxycycline
dyspnea
matrix metalloproteinase
respiratory function tests
Online Access:http://www.thoracicmedicine.org/article.asp?issn=1817-1737;year=2011;volume=6;issue=4;spage=221;epage=226;aulast=Dalvi

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http://www.thoracicmedicine.org/article.asp?issn=1817-1737;year=2011;volume=6;issue=4;spage=221;epage=226;aulast=Dalvi

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