Label-free drug response evaluation of human derived tumor spheroids using three-dimensional dynamic optical coherence tomography

Abstract This study aims at demonstrating label-free drug-response-patterns assessment of different tumor spheroids and drug types by dynamic optical coherence tomography (D-OCT). The study involved human breast cancer (MCF-7) and colon cancer (HT-29) spheroids. The MCF-7 and HT-29 spheroids were tr...

Full description

Bibliographic Details
Main Authors: Ibrahim Abd El-Sadek, Larina Tzu-Wei Shen, Tomoko Mori, Shuichi Makita, Pradipta Mukherjee, Antonia Lichtenegger, Satoshi Matsusaka, Yoshiaki Yasuno
Format: Article
Language:English
Published: Nature Portfolio 2023-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-41846-3