Molecular pathways associated with blood pressure and hexadecanedioate levels.

The dicarboxylic acid hexadecanedioate is associated with increased blood pressure (BP) and mortality in humans and feeding it to rats raises BP. Here we aim to characterise the molecular pathways that influence levels of hexadecanedioate linked to BP regulation, using genetic and transcriptomic stu...

Full description

Bibliographic Details
Main Authors: Cristina Menni, Sarah J Metrustry, Georg Ehret, Anna F Dominiczak, Phil Chowienczyk, Tim D Spector, Sandosh Padmanabhan, Ana M Valdes
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5389832?pdf=render