A directed approach for the identification of transcripts harbouring the spliced leader sequence and the effect of trans-splicing knockdown in Schistosoma mansoni

A directed approach for the identification of transcripts harbouring the spliced leader sequence and the effect of trans-splicing knockdown in Schistosoma mansoni

Schistosomiasis is a major neglected tropical disease caused by trematodes from the genus Schistosoma. Because schistosomes exhibit a complex life cycle and numerous mechanisms for regulating gene expression, it is believed that spliced leader (SL) trans-splicing could play an important role in the...

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Bibliographic Details
Main Authors: Marina de Moraes Mourao, Maina Bitar, Francisco Pereira Lobo, Ana Paula Peconick, Priscila Grynberg, Francisco Prosdocimi, Michael Waisberg, Gustavo Coutinho Cerqueira, Andrea Mara Macedo, Carlos Renato Machado, Timothy Yoshino, Gloria Regina Franco
Format: Article
Language:English
Published: Fundação Oswaldo Cruz (FIOCRUZ) 2013-09-01
Series:Memorias do Instituto Oswaldo Cruz
Subjects:
spliced leader
trans-splicing
RNA interference
Schistosoma mansoni
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762013000600707&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762013000600707&lng=en&tlng=en

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