Death receptor 3 is involved in preeclampsia through regulating placental trophoblast cell physiology by inactivating the PI3K/AKT pathway

Abstract Background Preeclampsia (PE) is a pregnancy related disease that affects about 5% of pregnancies. Death receptor 3 (DR3) expression is significantly elevated in both placental tissue and plasma of PE patients. However, whether DR3 was involved in trophoblasts in pathogenesis of PE are not w...

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Bibliographic Details
Main Authors: Cheng Yin, Jiahui Wang, Yu Zhang, Xinping Zhang, Wei Zhao, Yanxiang Shen, Shi Liu, Su Liu
Format: Article
Language:English
Published: Wiley 2023-09-01
Series:Immunity, Inflammation and Disease
Subjects:
Online Access:https://doi.org/10.1002/iid3.995