The E-box motif in the proximal ABCA1 promoter mediates transcriptional repression of the ABCA1 gene

The E-box motif in the proximal ABCA1 promoter mediates transcriptional repression of the ABCA1 gene

To identify regulatory elements in the proximal human ATP-binding cassette transporter A1 (hABCA1) gene promoter we transfected RAW cells with plasmids containing mutations in the E-box, AP1, and liver X receptor (LXR) elements as well as the two Sp1 motifs. Point mutations in either Sp1 site or in...

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Bibliographic Details
Main Authors: Xiao-Ping Yang, Lita A. Freeman, Catherine L. Knapper, Marcelo J.A. Amar, Alan Remaley, H. Bryan Brewer, Jr., Silvia Santamarina-Fojo
Format: Article
Language:English
Published: Elsevier 2002-02-01
Series:Journal of Lipid Research
Subjects:
high density lipoproteins
ATP-binding cassette transporter
E-box
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520301723

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http://www.sciencedirect.com/science/article/pii/S0022227520301723

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