The vascular basement membrane as "soil" in brain metastasis.
Brain-specific homing and direct interactions with the neural substance are prominent hypotheses for brain metastasis formation and a modern manifestation of Paget's "seed and soil" concept. However, there is little direct evidence for this "neurotropic" growth in vivo. In c...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2009-06-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC2689678?pdf=render |