The impact of early life maternal deprivation on the perineuronal nets in the prefrontal cortex and hippocampus of young adult rats

The impact of early life maternal deprivation on the perineuronal nets in the prefrontal cortex and hippocampus of young adult rats

Early life stress negatively impacts brain development and affects structure and function of parvalbumin immunopositive (PV+) inhibitory neurons. Main regulators of PV+ interneurons activity and plasticity are perineuronal nets (PNNs), an extracellular matrix formation that enwraps PV+ interneurons...

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Bibliographic Details
Main Authors: Ana Jakovljevic, Gorana Agatonovic, Dubravka Aleksic, Milan Aksic, Gebhard Reiss, Eckart Förster, Antonios Stamatakis, Igor Jakovcevski, Joko Poleksic
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
perineuronal nets
interneurons
maternal deprivation
early life stress
prefrontal cortex
hippocampus
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2022.982663/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2022.982663/full

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