Increased expression of miR-194-5p through the circPVRL3/miR-194-5p/SOCS2 axis promotes proliferation and metastasis in pancreatic ductal adenocarcinoma by activating the PI3K/AKT signaling pathway

Increased expression of miR-194-5p through the circPVRL3/miR-194-5p/SOCS2 axis promotes proliferation and metastasis in pancreatic ductal adenocarcinoma by activating the PI3K/AKT signaling pathway

Abstract Background MicroRNAs (miRNAs), as an indispensable type of non-coding RNA (ncRNA), participate in diverse biological processes. However, the specific regulatory mechanism of certain miRNAs in pancreatic ductal adenocarcinoma (PDAC) remains unclear. Methods The expression of miR-194-5p in PD...

Full description

Bibliographic Details
Main Authors: Bojing Chi, Yao Zheng, Fuming Xie, Wen Fu, Xianxing Wang, Jianyou Gu, Jiali Yang, Jingyang Yin, Lei Cai, Peng Tang, Jianbo Li, Shixiang Guo, Huaizhi Wang
Format: Article
Language:English
Published: BMC 2022-12-01
Series:Cancer Cell International
Subjects:
Circular RNA
miR-194-5p
Cell cycle
Pancreatic ductal adenocarcinoma
Online Access:https://doi.org/10.1186/s12935-022-02835-0

Internet

https://doi.org/10.1186/s12935-022-02835-0

Similar Items