Harnessing Apoptotic Cell Clearance to Treat Autoimmune Arthritis

Harnessing Apoptotic Cell Clearance to Treat Autoimmune Arthritis

Early-stage apoptotic cells possess immunomodulatory properties. Proper apoptotic cell clearance during homeostasis has been shown to limit subsequent immune responses. Based on these observations, early-stage apoptotic cell infusion has been used to prevent unwanted inflammatory responses in differ...

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Bibliographic Details
Main Authors: Philippe Saas, Francis Bonnefoy, Eric Toussirot, Sylvain Perruche
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-10-01
Series:Frontiers in Immunology
Subjects:
apoptotic cells
rheumatoid arthritis
collagen-induced arthritis
macrophages
regulatory T cells
efferocytosis
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01191/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2017.01191/full

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