Anticentromere antibody induced by immunization with centromere protein and Freund’s complete adjuvant may interfere with mouse early-stage embryo

Abstract Background Anticentromere antibody (ACA) is a member of the antinuclear antibody spectrum (ANAs) which has been speculated to be associated with subfertility. Thus, the present study aimed to investigate the induction of ACA production and its potential interference with early-stage embryos...

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Bibliographic Details
Main Authors: Hanyan Liu, Yufen Zhang, Haiying Liu, Qing Huang, Ying Ying
Format: Article
Language:English
Published: BMC 2021-08-01
Series:Reproductive Biology and Endocrinology
Subjects:
Online Access:https://doi.org/10.1186/s12958-021-00813-1