The metabolism of cells regulates their sensitivity to NK cells depending on p53 status

The metabolism of cells regulates their sensitivity to NK cells depending on p53 status

Abstract Leukemic cells proliferate faster than non-transformed counterparts. This requires them to change their metabolism to adapt to their high growth. This change can stress cells and facilitate recognition by immune cells such as cytotoxic lymphocytes, which express the activating receptor Natu...

Full description

Bibliographic Details
Main Authors: Sana Belkahla, Joaquin Marco Brualla, Alexis Fayd’herbe de Maudave, Paolo Falvo, Nerea Allende-Vega, Michael Constantinides, Abrar Ul Haq Khan, Lois Coenon, Catherine Alexia, Giulia Mitola, Paul Massa, Stefania Orecchioni, Francesco Bertolini, Wissem Mnif, Javier Hernandez, Alberto Anel, Martin Villalba
Format: Article
Language:English
Published: Nature Portfolio 2022-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-07281-6

Internet

https://doi.org/10.1038/s41598-022-07281-6

Similar Items